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A block zero-padding method based on DCFT for L1 parameter estimations in weak signal and high dynamic

Chao WU,Lu-ping XU,Hua ZHANG,Wen-bo ZHAO

Frontiers of Information Technology & Electronic Engineering 2015, Volume 16, Issue 9,   Pages 796-804 doi: 10.1631/FITEE.1500058

Abstract: Weak L1 signal acquisition in a high dynamic environment primarily faces a challenge: the integrationzero-padding method based on a discrete chirp-Fourier transform (DCFT) for parameter estimations in weaksignal and high dynamic environments.In this way, the post-correlation signal is coherently post-integrated with the bit sequence strippedmethod can precisely detect the high dynamic parameters in lower SNR when the length of the received signal

Keywords： Threshold detection     Discrete chirp-Fourier transform     Block zero-padding     High dynamic     Weak L1 signal    

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Extended stochastic resonance (SR) and its applications in weak mechanical signal processing

Niaoqing HU, Min CHEN, Guojun QIN, Lurui XIA, Zhongyin PAN, Zhanhui FENG,

Frontiers of Mechanical Engineering 2009, Volume 4, Issue 4,   Pages 450-461 doi: 10.1007/s11465-009-0072-3

Abstract: early as possible, one of the most important strategies is to apply more progressive techniques during signalThis paper presents a method based on stochastic resonance (SR) to detect weak fault signal.Then, the frequency range of the weak signals that the SR model can detect is extended through a typeFinally, the method is applied to extract the weak characteristic component from heavy noise to indicate

Keywords： extended stochastic resonance (SR)     stability analysis of SR     scale transform     weak signal detection     incipient    

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PD-1/PD-L1 blockade in cervical cancer: current studies and perspectives

Yumeng Wang, Guiling Li

Frontiers of Medicine 2019, Volume 13, Issue 4,   Pages 438-450 doi: 10.1007/s11684-018-0674-4

Abstract: Checkpoint blockades targeting the PD-1/PD-L1 axis have achieved effective clinical responses with acceptableIn this review, we summarize recent advances in our understanding of the PD-1/PD-L1 signaling pathway, including the expression patterns of PD-1/PD-L1 and potential PD-1/PD-L1-related therapeutic strategies

Keywords： PD-1     PD-L1     immune checkpoint blockade antibody     immunotherapy     cervical cancer    

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Metabolic interventions combined with CTLA-4 and PD-1/PD-L1 blockade for the treatment of tumors: mechanisms

Frontiers of Medicine   Pages 805-822 doi: 10.1007/s11684-023-1025-7

Abstract: To date, immune checkpoint inhibitors (ICIs) of CTLA-4 and PD-1/PD-L1 represent the main class of immunotherapyBlockade of CTLA-4 and PD-1/PD-L1 has shown remarkable efficacy in several specific types of cancers,generalized mechanism of targeting cancer metabolism at three crucial immune checkpoints (CTLA-4, PD-1,and PD-L1) to influence ICB therapy and propose potential combined immunotherapeutic strategies co-targeting

Keywords： CTLA-4     PD-1     PD-L1     immune checkpoint blockade (ICB)     metabolic reprogramming     combined tumor therapeutic    

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Activation of phagocytosis by immune checkpoint blockade

Chia-Wei Li, Yun-Ju Lai, Jennifer L. Hsu, Mien-Chie Hung

Frontiers of Medicine 2018, Volume 12, Issue 4,   Pages 473-480 doi: 10.1007/s11684-018-0657-5

Abstract: One mechanism inhibiting the innate response is the presence of the macrophage inhibitory molecule, signalOn the basis of a recently discovered programmed death protein 1 (PD-1) in TAMs, we discuss the potential

Keywords： CD47     PD-1     PD-L1     immunotherapy     TAM     phagocytosis     macrophage    

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Influence and related mechanism of Retn gene expression on glucose uptake in 3T3-L1 cells

LI Yahui, DONG Shiyuan, YU Chao, JIANG Yu, LI Huaixing, SUN Shuhan

Frontiers of Medicine 2007, Volume 1, Issue 3,   Pages 269-273 doi: 10.1007/s11684-007-0051-1

Abstract: the influence and the related mechanism of the gene on glucose uptake and insulin resistance in 3T3-L1Radioimmunoassay was used to determine glucose uptake in 3T3-L1 cells with different gene expressionRT-PCR analysis were used to determine the mRNA levels of several glucose transport proteins in 3T3-L1The mRNA expression of two signal proteins PI-3K and AKT-2 decreased and the other two signal proteins, GSK-3 and p38MAPK, increased with overexpression in 3T3-L1 cells.

Keywords： 3T3-L1     influence     resistance     receptor substrate-1     transport    

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The Technical Scheme and Key Equipment for Solving the Difficult Technical Problems of Underground Radio Communications

Situ Mengtian

Strategic Study of CAE 2001, Volume 3, Issue 7,   Pages 64-69

Abstract:

Two difficult tedhnical problems in underground radio communications, i.e. weak signal reception andThe design scheme of the telegraph terminal used for weak signal reception and counter lightning pulses

Keywords： underground radio communications     weak signal reception     counter lightning interference    

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Image-based traffic signal control via world models Research Article

Xingyuan DAI, Chen ZHAO, Xiao WANG, Yisheng LV, Yilun LIN, Fei-Yue WANG

Frontiers of Information Technology & Electronic Engineering 2022, Volume 23, Issue 12,   Pages 1795-1813 doi: 10.1631/FITEE.2200323

Abstract: To this end, an effective prediction model is needed for signal controllers.

Keywords： Traffic signal control     Traffic prediction     Traffic world model     Reinforcement learning    

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Analysis and stabilization control of a voltage source controlled wind farm under weak grid conditions

Frontiers in Energy 2022, Volume 16, Issue 6,   Pages 943-955 doi: 10.1007/s11708-021-0793-5

Abstract: This paper investigates and discusses the interaction stability issues of a wind farm with weak gridHowever, when it is applied to multiple WTs within a wind farm, its weak-grid performance regarding theof a stability margin quantification index, not only the interactions between the wind farm and the weak

Keywords： weak grids     voltage source (VS) control     wind turbine (WT)     stabilization control     wind farm     inertial    

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Hao Wang, Zhi-yuan Wang, Ben-dong Wang, Zhong-he Jin, John L. Crassidis,roger@zju.edu.cn

Frontiers of Information Technology & Electronic Engineering 2021, Volume 22, Issue 2,   Pages 141-286 doi: 10.1631/FITEE.1900358

Abstract: s are widely used in attitude-determination and control systems of satellites. The main deficiency of static s is the requirement of a small field of view (FOV). A typical FOV for a static is about 20° to 30°, which may not be sufficient for low-Earth-orbiting s. A novel compact with an FOV of nearly 180° is developed here. The Earth sensor comprises a panoramic annular lens (PAL) and an off-the-shelf camera with an uncooled complementary-metal-oxide-semiconductor (CMOS) infrared sensor. PAL is used to augment FOV so as to obtain a complete infrared image of the Earth from low-Earth-orbit. An algorithm is developed to compensate for the distortion caused by PAL and to calculate the vector of the Earth. The new is compact with low power consumption and high precision. Simulated images and on-orbit infrared images obtained via the ZDPS-2 are used to assess the performance of the new . Experiments show that the accuracy of the Earth sensor is about 0.032°.

Keywords： Infrared Earth sensor     Micro-satellite     Attitude determination system    

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Molecular classification and precision therapy of cancer: immune checkpoint inhibitors

Yingyan Yu

Frontiers of Medicine 2018, Volume 12, Issue 2,   Pages 229-235 doi: 10.1007/s11684-017-0581-0

Abstract: refractory Hodgkin lymphoma, and urothelial carcinoma, all of which carry positive programmed death-1/programmed death-ligand 1 biomarkers.

Keywords： molecular classification     precision medicine     pembrolizumab     PD-1/PD-L1     MSI-H    

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Enhancement of sludge gravitational thickening with weak ultrasound

Panyue ZHANG, Tian WAN, Guangming ZHANG

Frontiers of Environmental Science & Engineering 2012, Volume 6, Issue 5,   Pages 753-760 doi: 10.1007/s11783-011-0368-5

Abstract: of sonication on enhancing the sludge gravitational thickening with very low energy dose, so called “weakResults showed that weak sonication significantly changed the sludge settlability and the main mechanismWeak sonication (<680 kJ·kg DS) improved the sludge gravitational thickening while high ultrasonic energyWeak sonication could substitute expensive polyelectrolyte coagulant for sludge thickening.Combination of weak sonication and polyelectrolyte could further reduce the settling time to 6 h.

Keywords： activated sludge     sonication     settlability     dry weight     extracellular polymeric substances     polyelectrolyte    

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of the agglomeration of crystals in the reactive crystallization of 5-(difluoromethoxy)-2-mercapto-1

Yongli WANG, Shuyuan MA, Xiaodong Lü, Chuang XIE

Frontiers of Chemical Science and Engineering 2012, Volume 6, Issue 4,   Pages 423-431 doi: 10.1007/s11705-012-1211-7

Abstract: 5-(Difluoromethoxy)-2-mercapto-1 -benzimidazole (DMB) was precipitated by adding acetic acid to the DMB

Keywords： 5-(difluoromethoxy)-2-mercapto-1H-benzimidazole (DMB)     reactive crystallization     agglomeration    

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Modeling and analysis of magnetic dipoles in weak magnetic field

WANG Zhaoxia, ZHANG Weimin, LIU Hongguang

Frontiers of Mechanical Engineering 2008, Volume 3, Issue 2,   Pages 222-225 doi: 10.1007/s11465-008-0028-z

Abstract: The formula to compute the normal component of the weak magnetic field is deduced based on the spatial

Keywords： geomagnetic     theory     important criterion     magnetic leakage     normal component    

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Stability analysis on Tingzikou gravity dam along deep-seated weak planes during earthquake

Weiping HE, Yunlong HE

Frontiers of Structural and Civil Engineering 2012, Volume 6, Issue 1,   Pages 69-75 doi: 10.1007/s11709-012-0146-x

Abstract: The stability of a gravity dam against sliding along deep-seated weak planes is a universal and importantThere is no recommended method for stability analysis of the dam on deep-seated weak planes under earthquakesearching a proper way to evaluate the seismic safety of the dam against sliding along deep-seated weakplanes and the probable failure modes of dam on deep-seated weak planes during earthquake.in the second mode, the dam together with part foundation will slide along the path consist of the weak

Keywords： gravity dam     deep-seated weak planes     stability against sliding     earthquake    

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Title Author Date Type Operation

A block zero-padding method based on DCFT for L1 parameter estimations in weak signal and high dynamic

Chao WU,Lu-ping XU,Hua ZHANG,Wen-bo ZHAO

Journal Article

Extended stochastic resonance (SR) and its applications in weak mechanical signal processing

Niaoqing HU, Min CHEN, Guojun QIN, Lurui XIA, Zhongyin PAN, Zhanhui FENG,

Journal Article

PD-1/PD-L1 blockade in cervical cancer: current studies and perspectives

Yumeng Wang, Guiling Li

Journal Article

Metabolic interventions combined with CTLA-4 and PD-1/PD-L1 blockade for the treatment of tumors: mechanisms

Journal Article

Activation of phagocytosis by immune checkpoint blockade

Chia-Wei Li, Yun-Ju Lai, Jennifer L. Hsu, Mien-Chie Hung

Journal Article

Influence and related mechanism of Retn gene expression on glucose uptake in 3T3-L1 cells

LI Yahui, DONG Shiyuan, YU Chao, JIANG Yu, LI Huaixing, SUN Shuhan

Journal Article

The Technical Scheme and Key Equipment for Solving the Difficult Technical Problems of Underground Radio Communications

Situ Mengtian

Journal Article

Image-based traffic signal control via world models

Xingyuan DAI, Chen ZHAO, Xiao WANG, Yisheng LV, Yilun LIN, Fei-Yue WANG

Journal Article

Analysis and stabilization control of a voltage source controlled wind farm under weak grid conditions

Journal Article

N

Hao Wang, Zhi-yuan Wang, Ben-dong Wang, Zhong-he Jin, John L. Crassidis,roger@zju.edu.cn

Journal Article

Molecular classification and precision therapy of cancer: immune checkpoint inhibitors

Yingyan Yu

Journal Article

Enhancement of sludge gravitational thickening with weak ultrasound

Panyue ZHANG, Tian WAN, Guangming ZHANG

Journal Article

of the agglomeration of crystals in the reactive crystallization of 5-(difluoromethoxy)-2-mercapto-1

Yongli WANG, Shuyuan MA, Xiaodong Lü, Chuang XIE

Journal Article

Modeling and analysis of magnetic dipoles in weak magnetic field

WANG Zhaoxia, ZHANG Weimin, LIU Hongguang

Journal Article

Stability analysis on Tingzikou gravity dam along deep-seated weak planes during earthquake

Weiping HE, Yunlong HE

Journal Article